Biotin and derivatives
Chem-Impex International, Inc. Biotinyl-e-aminocaproic acid-N-hydroxysuccinimide ester | 72040-63-2 | MFCD00065502 | 1G
Biotinyl-e-aminocaproic acid-N-hydroxysuccinimide ester, 72040-63-2, MFCD00065502, 1G
IBA LifeSciences Biotin powder; 5 g
Biotin is a water-soluble B-complex vitamin, also known as vitamin B7 or vitamin H. It binds to the biotin-binding pockets of streptavidin, Strep-Tactin, and Strep-TactinXT with different affinities. As a result, it allows the efficient elution of Strep-tagII or Twin-Strep-tag fusion proteins from Strep-TactinXT, while maintaining the reusability of the resin. It can be used for preparation of Strep-TactinXT elution buffer, Buffer BXT. In addition, biotin can be used for elution of biotinylated proteins from Strep-Tactin, where it binds irreversibly to the resin. Hence, Strep-Tactin cannot be regenerated in this kind of application.
Medchemexpress LLC Bz-(Me)Tz-NHS | 1454558-58-7 | MFCD00076258 | C₁₉H₂₀N₅O₅S | 25 MG
Bz-(Me)Tz-NHS is a click chemistry reagent that contains a methyltetrazine group. It functions as a 3rd generation Click-Linker for Cu-free click conjugation, primarily used in antibody-drug conjugate (ADC) related research.
- Contains a methyltetrazine group
- Functions as a 3rd generation Click-Linker
- Designed for Cu-free click conjugation
- Used in antibody-drug conjugate (ADC) related research
Medchemexpress LLC PC azido-PEG3-NHS carbonate ester | 1802907-96-5 | MFCD29052189 | 98.7% | 640.60 | C26H36N6O13 | 100 MG
PC Azido-PEG3-NHS carbonate ester is a photocleavable linker reagent that selectively labels primary amines on proteins, amine-modified oligonucleotides, and other amine-containing molecules. It contains an azide for bioorthogonal click chemistry and an N-hydroxysuccinimide (NHS) carbonate group for efficient coupling; the photocleavable moiety enables light-triggered release of attached cargos. Supplied at high purity for research use.
- Photocleavable linker enabling light-triggered release
- Reacts with primary amines via NHS carbonate chemistry
- Includes an azide for bioorthogonal click reactions
- High purity suitable for research applications
- Offered in multiple pack sizes, e.g., 100 mg
Medchemexpress LLC m-PEG16-NHS ester | 2563873-83-4 | 100mg
m-PEG16-NHS ester is a PEG derivative composed of an NHS ester that can be conjugated to amino acids or other molecules containing amino groups[1]
Medchemexpress LLC Mal-PEG8-NHS ester | 2055033-05-9 | 99.0% | 1 G
Mal-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. They exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- Molecular weight: 618.63
- Molecular formula: C27H42N2O14
- Purity: 98.96%
- Appearance: Colorless to light yellow viscous liquid
- Soluble in DMSO: ≥ 100 mg/mL
Medchemexpress LLC Biotin-EDA | 111790-37-5 | 97.5% | 100 MG
Biotin-EDA is an alkyl chain-based PROTAC linker used in the synthesis of PROTACs, which consist of two different ligands connected by a linker. These PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Alkyl chain-based PROTAC linker
- Used in the synthesis of PROTACs
- PROTACs leverage the intracellular ubiquitin-proteasome system
- PROTACs selectively degrade target proteins